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Assess and treat comorbid disorders eg, depression , substance use disorders.

Medical management of adult transsexual persons.

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Subjects had been treated with cross-sex hormones for a total of 10, patient-years. Only a minority of children diagnosed with gender dysphoria remain gender dysphoric as adults.

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When sex labeling and rearing are confusing eg, in cases of ambiguous genitals or genetic syndromes altering genital appearance, such as androgen insensitivity syndromes , children may become uncertain about their gender identity or role, although the level of importance of environmental factors remains controversial. Lengthening of the female urethra to male dimensions may cause urethral fistulae, urethral strictures and meatal stenoses.

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